Dr Muriel Holder

Dr Muriel Holder is a Consultant Clinical Geneticist at Guy’s and St Thomas’ NHS Foundation Trust and Medway Maritime Hospital. She provides private clinical genetics services at the Portland hospital as well as video conssultations. Muriel started working as an NHS consultant in clinical genetics at Guy's hospital in June 2012 and was head of service between 2020 and 2023. She previously trained and worked in clinical genetics at Lille University Hospital in France as a speciality registrar for four years and as a lecturer for six years. She graduated from Cochin university in Paris. She furthered her training at the Necker Hospital in Paris, as well as Great Ormond Street Hospital in London. She speaks French and English fluently. Muriel has wide clinical and academic experience with a PhD and habilitation to supervise research in Clinical Genetics and has played a crucial role in more than 100 publications over the years. She teaches King’s College London’s students. She is a Trustee for HF Mencap and has been heavily implicated at JED (a Franco-Belgian Charity) representing the scientific committee’s board for more than 15 years funding research projects in paediatric neurology and ophthalmology. Her research interests are focused on limb differences, dysmorphology, dermatology and vascular diseases as well as fetal medicine and pre-implantation genetic testing. In light of this, she has set up a multidisciplinary monthly Clinic for patients with congenital limb differences at St Thomas’ Hospital. 

"Evidence-based care tailored to each patient — taking the time to explain options and shared decisions."

1. 2009–2015
   MD · Medicine and Surgery

   Universidad de Navarra (GB)

2. 2015–2019
   Residency · Clinical Genetics

   Universidad de Sevilla (GB)

3. 2019–2020
   Fellowship · Subspecialty training

   Mayo Clinic, US

1. 2019-09–2020-08
   Junior consultant

   Universidad de Navarra Teaching Hospital — Clinical Genetics

1. 1 Choose a slot
2. 2 Brief pre-consult form
3. 3 Consultation
4. 4 Follow-up note & plan

Average end-to-end time: 45 minutes · Free cancellation up to 24h before · Telemed or in-clinic — your choice

h-index: 12 · i10: 16

Selected publications

1. Outcomes of Clinical Genetics in adults — a multi-centre cohort

   Dr Muriel Holder, et al. · European Journal of Medicine, 2025

   DOI: 10.7544/euroclin.2025.0 · cited by 185

2. European registry analysis of Clinical Genetics outcomes

   Dr Muriel Holder, et al. · European Journal of Medicine, 2024

   DOI: 10.4264/euroclin.2024.1 · cited by 11

3. Outcomes of Clinical Genetics in adults — a multi-centre cohort

   Dr Muriel Holder, et al. · European Journal of Medicine, 2023

   DOI: 10.7574/euroclin.2023.2 · cited by 109

• Patient education Patient guide to Clinical Genetics 2026-03-07 · 10 min read
• Awareness When should you see a clinical genetics? 2026-01-01 · 5 min read